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Diet? Check. Exercise? Check. Statin? Check. Bad cholesterol still too high?

Lowering bad cholesterol can be a never-ending cycle

    Stuck in a cycle of diet, exercise, and a statin without
   the results you need? Adding nonstatin NEXLETOL—just 1 pill,
  once a day—may be the edge you need if you have known
 heart disease or an inherited condition that causes high levels
of bad cholesterol. Learn more.

Stuck in a cycle of diet, exercise, and a statin without the results you need? Adding nonstatin NEXLETOL—just 1 pill, once a day—may be the edge you need if you have known heart disease or an inherited condition that causes high levels of bad cholesterol. Learn more.

Have questions about NEXLETOL? Call 1-833-NEXLETOL (1-833-639-5386) or see frequently asked questions.

What is NEXLETOL?

NEXLETOL is a prescription medicine used, along with diet and other lipid-lowering medicines, in the treatment of adults who need additional lowering of “bad” cholesterol (LDL-C) and have:

  • heterozygous familial hypercholesterolemia (HeFH), an inherited condition that causes high levels of LDL-C, and/or
  • known cardiovascular disease

It is not known if NEXLETOL can decrease problems related to high cholesterol, such as heart attacks or stroke.

IMPORTANT SAFETY INFORMATION

What should I tell my doctor before taking NEXLETOL?

Tell your doctor if you:

  • have, or have ever had, gout
  • have, or have ever had, tendon problems
  • are pregnant or breastfeeding, or may become pregnant or plan to breastfeed
  • have severe kidney or liver problems
  • are taking simvastatin or pravastatin

What is the most important safety information I should know about NEXLETOL?

NEXLETOL can cause side effects that can become serious, including:

  • high levels of uric acid in the blood, which can lead to gout, a painful joint condition. Call your doctor if you have any of the following symptoms:
  • severe foot pain, especially in the toe joint
  • warm joints
  • swelling
  • tender joints
  • joint redness
  • tendon problems: Stop taking NEXLETOL immediately and get medical help right away if you get any of the following signs or symptoms of tendon rupture:
  • hear or feel a snap or pop in a tendon area
  • bruising right after an injury in a tendon area
  • unable to move the affected area or put weight on the affected area

What are the common side effects of NEXLETOL?

Tell your doctor right away about any side effect you experience. NEXLETOL can cause side effects, including:

  • symptoms of the common cold or flu
  • muscle spasms
  • back pain
  • pain in the legs or arms
  • stomach pain

Your doctor may check your blood for side effects that you might not be able to feel.

These are not all the possible side effects of NEXLETOL. For more information, ask your doctor or pharmacist.

What form does NEXLETOL come in?

NEXLETOL is a tablet that you take by mouth. It contains 180 mg of bempedoic acid.

Can I take NEXLETOL with other medicines?

For lowering cholesterol, NEXLETOL is often taken with other medicines, including a group of medicines called statins. For two statins, simvastatin and pravastatin, your doctor may change the dose if you also take NEXLETOL. Before taking NEXLETOL, tell your doctor if you take any of the following medicines:

  • simvastatin
  • pravastatin

The risk information provided here is not comprehensive. To learn more, talk about NEXLETOL with your doctor or pharmacist. The FDA-approved product labelling can be found at NEXLETOL.com or 1-833-377-7633.

You may report side effects to the FDA at 1-800-FDA-1088, or at www.fda.gov/medwatch. You may also report side effects to Esperion at 1-833-377-7633.

NEXLETOL is available by prescription only.

Please see full Prescribing Information, including Patient Product Information.

EXPAND

What is NEXLETOL?

NEXLETOL is a prescription medicine used, along with diet and other lipid-lowering medicines, in the treatment of adults who need additional lowering of “bad” cholesterol (LDL-C) and have:

  • heterozygous familial hypercholesterolemia (HeFH), an inherited condition that causes high levels of LDL-C, and/or
  • known cardiovascular disease

It is not known if NEXLETOL can decrease problems related to high cholesterol, such as heart attacks or stroke.

IMPORTANT SAFETY INFORMATION

What should I tell my doctor before taking NEXLETOL?

Tell your doctor if you:

  • have, or have ever had, gout
  • have, or have ever had, tendon problems
  • are pregnant or breastfeeding, or may become pregnant or plan to breastfeed
  • have severe kidney or liver problems
  • are taking simvastatin or pravastatin

What is the most important safety information I should know about NEXLETOL?

NEXLETOL can cause side effects that can become serious, including:

  • high levels of uric acid in the blood, which can lead to gout, a painful joint condition. Call your doctor if you have any of the following symptoms:
  • severe foot pain, especially in the toe joint
  • warm joints
  • swelling
  • tender joints
  • joint redness
  • tendon problems: Stop taking NEXLETOL immediately and get medical help right away if you get any of the following signs or symptoms of tendon rupture:
  • hear or feel a snap or pop in a tendon area
  • bruising right after an injury in a tendon area
  • unable to move the affected area or put weight on the affected area

What are the common side effects of NEXLETOL?

Tell your doctor right away about any side effect you experience. NEXLETOL can cause side effects, including:

  • symptoms of the common cold or flu
  • muscle spasms
  • back pain
  • pain in the legs or arms
  • stomach pain

Your doctor may check your blood for side effects that you might not be able to feel.

These are not all the possible side effects of NEXLETOL. For more information, ask your doctor or pharmacist.

What form does NEXLETOL come in?

NEXLETOL is a tablet that you take by mouth. It contains 180 mg of bempedoic acid.

Can I take NEXLETOL with other medicines?

For lowering cholesterol, NEXLETOL is often taken with other medicines, including a group of medicines called statins. For two statins, simvastatin and pravastatin, your doctor may change the dose if you also take NEXLETOL. Before taking NEXLETOL, tell your doctor if you take any of the following medicines:

  • simvastatin
  • pravastatin

The risk information provided here is not comprehensive. To learn more, talk about NEXLETOL with your doctor or pharmacist. The FDA-approved product labelling can be found at NEXLETOL.com or 1-833-377-7633.

You may report side effects to the FDA at 1-800-FDA-1088, or at www.fda.gov/medwatch. You may also report side effects to Esperion at 1-833-377-7633.

NEXLETOL is available by prescription only.

Please see full Prescribing Information, including Patient Product Information.