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Start lowering your bad cholesterol with our support.

If you have been prescribed NEXLIZET or NEXLETOL, we are here to help.

We’ve created a patient support program called NEXSTEP to give you more of the tools and resources you will need. This program includes information about how bad cholesterol can affect your heart health. NEXSTEP also offers representatives who can help you activate and use your Co-Pay Card if you have commercial insurance.

If you have not been prescribed NEXLIZET or NEXLETOL and are still planning to talk to your doctor, we also have a support option for you. You just need to enroll below!

ALL FIELDS ARE REQUIRED UNLESS OTHERWISE NOTED. MUST BE 18 YEARS OR OLDER AND A RESIDENT OF THE UNITED STATES.

As someone who has been diagnosed with high bad cholesterol, please tell us which best describes you (select one):

I have a prescription for NEXLIZET

I have a prescription for NEXLETOL

I do not have a prescription but I am interested in learning more


What are NEXLIZET and NEXLETOL?

  • Along with a diet:
    • NEXLETOL is used, with other cholesterol-lowering medicines, or alone when use with other cholesterol-lowering medicines is not possible, to reduce low-density lipoprotein (LDL, or bad cholesterol) in adults with high blood cholesterol levels called primary hyperlipidemia, including a type of high blood cholesterol called heterozygous familial hypercholesterolemia (HeFH).
    • NEXLIZET is used, with or without other cholesterol-lowering medicines, to reduce low-density lipoprotein (LDL, or bad cholesterol) in adults with high blood cholesterol levels called primary hyperlipidemia, including a type of high cholesterol called heterozygous familial hypercholesterolemia (HeFH).
  • The bempedoic acid portion of NEXLIZET and NEXLETOL is used to lower the risk of heart attack and heart procedures like stent placement or bypass surgery, in adults who are unable to take recommended statin treatment (a cholesterol-lowering medicine), or are not taking a statin, who:
    • have known heart disease, or
    • are at high risk for heart disease but without known heart disease.

IMPORTANT SAFETY INFORMATION

Do not take NEXLIZET if you are allergic to ezetimibe or bempedoic acid, or any ingredients in NEXLIZET or NEXLETOL. If you have any of the following signs and symptoms of a serious allergic reaction, call your healthcare provider or go to the nearest hospital emergency room:

  • swelling of your face, lips, mouth, or tongue
  • wheezing
  • severe itching
  • fast heartbeat or pounding in your chest
  • trouble breathing
  • skin rashes, redness, or swelling
  • dizziness or fainting

What should I tell my healthcare provider before taking NEXLIZET or NEXLETOL?

Tell your healthcare provider if you:

  • have, or had, gout
  • have, or had, tendon problems
  • are pregnant or breastfeeding or may become pregnant or plan to breastfeed. It is not known if NEXLIZET or NEXLETOL passes into your breastmilk
  • have severe kidney or severe liver problems

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Especially tell your healthcare provider if you take or plan to take simvastatin or pravastatin, as taking either with bempedoic acid may increase your risk of developing muscle pain or weakness. If you take NEXLIZET, tell your doctor if you take cyclosporine, fibrates, or cholestyramine.

What is the most important safety information I should know about NEXLIZET and NEXLETOL?

NEXLIZET and NEXLETOL can cause serious side effects, including:

  • increased levels of uric acid in the blood, which can lead to gout, a painful joint condition. Call your doctor if you have any of the following symptoms: severe foot pain especially in the toe joint, warm joints, swelling, tender joints or joint redness.
  • tendon rupture or injury. Tendon problems can happen in people who take bempedoic acid, one of the medicines in NEXLIZET or NEXLETOL. The risk of getting tendon problems while you take NEXLIZET or NEXLETOL is higher if you: are over 60 years of age, are taking steroids, are taking antibiotics called fluoroquinolones, have renal failure, or have had tendon problems in the past. Stop taking NEXLIZET or NEXLETOL immediately and get medical help if you experience signs of tendon rupture such as snap or pop in tendon area, bruising after an injury in a tendon area, or unable to move or put weight on the affected area.

The most common side effects in patients with primary hyperlipidemia:

  • NEXLETOL includes symptoms of the common cold or flu-like symptoms, muscle spasms, back pain, stomach pain, bronchitis, pain in shoulder, legs, or arms, anemia and increased liver enzymes.
  • NEXLIZET includes symptoms of the common cold or flu-like symptoms, muscle spasms, back pain, stomach pain, bronchitis, pain in shoulder, legs, or arms, anemia, increased liver enzymes, diarrhea, joint pain, swelling of sinuses and fatigue.

The most common side effects of bempedoic acid, a component of NEXLIZET and NEXLETOL, in patients with heart problems include kidney problems, anemia, increased liver enzymes, muscle spasms, and gallstones.

These are not all the possible side effects of NEXLIZET and NEXLETOL. For more information, ask your healthcare provider or pharmacist for more information.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see full Prescribing Information for NEXLIZET and NEXLETOL, including Patient Product Information for NEXLIZET and NEXLETOL.

What are NEXLIZET and NEXLETOL?

  • Along with a diet:
    • NEXLETOL is used, with other cholesterol-lowering medicines, or alone when use with other cholesterol-lowering medicines is not possible, to reduce low-density lipoprotein (LDL, or bad cholesterol) in adults with high blood cholesterol levels called primary hyperlipidemia, including a type of high blood cholesterol called heterozygous familial hypercholesterolemia (HeFH).
    • NEXLIZET is used, with or without other cholesterol-lowering medicines, to reduce low-density lipoprotein (LDL, or bad cholesterol) in adults with high blood cholesterol levels called primary hyperlipidemia, including a type of high cholesterol called heterozygous familial hypercholesterolemia (HeFH).
  • The bempedoic acid portion of NEXLIZET and NEXLETOL is used to lower the risk of heart attack and heart procedures like stent placement or bypass surgery, in adults who are unable to take recommended statin treatment (a cholesterol-lowering medicine), or are not taking a statin, who:
    • have known heart disease, or
    • are at high risk for heart disease but without known heart disease.

IMPORTANT SAFETY INFORMATION

Do not take NEXLIZET if you are allergic to ezetimibe or bempedoic acid, or any ingredients in NEXLIZET or NEXLETOL. If you have any of the following signs and symptoms of a serious allergic reaction, call your healthcare provider or go to the nearest hospital emergency room:

  • swelling of your face, lips, mouth, or tongue
  • wheezing
  • severe itching
  • fast heartbeat or pounding in your chest
  • trouble breathing
  • skin rashes, redness, or swelling
  • dizziness or fainting

What should I tell my healthcare provider before taking NEXLIZET or NEXLETOL?

Tell your healthcare provider if you:

  • have, or had, gout
  • have, or had, tendon problems
  • are pregnant or breastfeeding or may become pregnant or plan to breastfeed. It is not known if NEXLIZET or NEXLETOL passes into your breastmilk
  • have severe kidney or severe liver problems

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Especially tell your healthcare provider if you take or plan to take simvastatin or pravastatin, as taking either with bempedoic acid may increase your risk of developing muscle pain or weakness. If you take NEXLIZET, tell your doctor if you take cyclosporine, fibrates, or cholestyramine.

What is the most important safety information I should know about NEXLIZET and NEXLETOL?

NEXLIZET and NEXLETOL can cause serious side effects, including:

  • increased levels of uric acid in the blood, which can lead to gout, a painful joint condition. Call your doctor if you have any of the following symptoms: severe foot pain especially in the toe joint, warm joints, swelling, tender joints or joint redness.
  • tendon rupture or injury. Tendon problems can happen in people who take bempedoic acid, one of the medicines in NEXLIZET or NEXLETOL. The risk of getting tendon problems while you take NEXLIZET or NEXLETOL is higher if you: are over 60 years of age, are taking steroids, are taking antibiotics called fluoroquinolones, have renal failure, or have had tendon problems in the past. Stop taking NEXLIZET or NEXLETOL immediately and get medical help if you experience signs of tendon rupture such as snap or pop in tendon area, bruising after an injury in a tendon area, or unable to move or put weight on the affected area.

The most common side effects in patients with primary hyperlipidemia:

  • NEXLETOL includes symptoms of the common cold or flu-like symptoms, muscle spasms, back pain, stomach pain, bronchitis, pain in shoulder, legs, or arms, anemia and increased liver enzymes.
  • NEXLIZET includes symptoms of the common cold or flu-like symptoms, muscle spasms, back pain, stomach pain, bronchitis, pain in shoulder, legs, or arms, anemia, increased liver enzymes, diarrhea, joint pain, swelling of sinuses and fatigue.

The most common side effects of bempedoic acid, a component of NEXLIZET and NEXLETOL, in patients with heart problems include kidney problems, anemia, increased liver enzymes, muscle spasms, and gallstones.

These are not all the possible side effects of NEXLIZET and NEXLETOL. For more information, ask your healthcare provider or pharmacist for more information.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see full Prescribing Information for NEXLIZET and NEXLETOL, including Patient Product Information for NEXLIZET and NEXLETOL.