Need help paying for treatment
and getting started?

A patient may be eligible for the NEXLIZET & NEXLETOL Co-Pay Card if they meet the eligibility criteria below:

• must be at least 18 years of age, AND
• has a valid prescription for NEXLIZET or NEXLETOL, AND
• has commercial prescription drug insurance, AND
• is a resident of the United States, including the District of Columbia but excluding territories (such as Puerto Rico and the US Virgin Islands), AND
• is not enrolled in any state-, federal-, or government-funded healthcare program, including but not limited to Medicare, Medicaid, Medigap, TRICARE of the Department of Defense, or the Department of Veterans Affairs (VA) healthcare program (collectively referred to as “Government Program”).

Should a patient have any change in insurance coverage or become enrolled in a Government Program during their enrollment in the NEXLIZET & NEXLETOL Co-Pay Card program, they must inform a NEXLIZET & NEXLETOL Co-Pay Card program representative and will no longer be eligible for the NEXLIZET & NEXLETOL Co-Pay Card program. Also, if a patient is enrolled in a Government Program, they may not use the NEXLIZET & NEXLETOL Co-Pay Card program even if they elect to be processed as a commercial or discount insurance plan patient.

NEXLIZET is a prescription medicine that contains 2 cholesterol-lowering medicines, bempedoic acid and ezetimibe.

• NEXLIZET is used, along with a healthy diet, with or without other cholesterol-lowering medicines, to reduce low-density lipoprotein (LDL, or bad cholesterol) in adults with high blood cholesterol levels called primary hyperlipidemia. This includes a type of high blood cholesterol called heterozygous familial hypercholesterolemia (HeFH)
• The bempedoic acid portion of NEXLIZET is used to lower the risk of heart attack and heart procedures, like stent placement or bypass surgery, in adults who are unable to take recommended statin treatment (a cholesterol-lowering medicine), or are not taking a statin, who have:
  • known heart disease, or
  • who are at high risk for heart disease but without known heart disease

NEXLETOL is a prescription medicine that contains a cholesterol-lowering medicine, bempedoic acid.

• NEXLETOL is used to lower the risk of heart attack and heart procedures, like stent placement or bypass surgery, in adults who are unable to take recommended statin treatment (a cholesterol-lowering medicine), or are not taking a statin, who have:
  • known heart disease, or
  • who are at high risk for heart disease but without known heart disease
• NEXLETOL is used, along with a healthy diet, with other cholesterol-lowering medicines or alone when use with other cholesterol-lowering medicines is not possible, to reduce low-density lipoprotein (LDL, or bad cholesterol) in adults with high blood cholesterol levels called primary hyperlipidemia. This includes a type of high blood cholesterol called heterozygous familial hypercholesterolemia (HeFH)

Do not take NEXLIZET if you are allergic to ezetimibe or bempedoic acid or NEXLETOL if you are allergic to bempedoic acid, or any ingredients in NEXLIZET or NEXLETOL. If you have any of the following signs and symptoms of a serious allergic reaction, call your healthcare provider or go to the nearest hospital emergency room:

• swelling of your face, lips, mouth, or tongue
• wheezing
• severe itching
• fast heartbeat or pounding in your chest
• trouble breathing
• skin rashes, redness, or swelling
• dizziness or fainting

NEXLIZET can cause serious side effects, including:

• increased levels of uric acid in the blood, which can lead to gout, a painful joint condition. Call your doctor if you have any of the following symptoms:
  • severe foot pain, especially in the toe joint
  • warm joints
  • swelling
  • tender joints
  • joint redness
• tendon rupture or injury. Tendon problems can happen in people who take bempedoic acid, one of the medicines in NEXLIZET. The risk of getting tendon problems while you take NEXLIZET is higher if you are over 60 years of age, are taking steroids, are taking antibiotics called fluoroquinolones, have renal failure, or have had tendon problems in the past. Stop taking NEXLIZET immediately and get medical help if you experience signs of tendon rupture, such as snap or pop in tendon area, bruising after an injury in a tendon area, or unable to move or put weight on the affected area

The most common side effects of NEXLIZET in people with high cholesterol include symptoms of the common cold or flu-like symptoms, muscle spasms, back pain, stomach pain, bronchitis, pain in shoulder, legs, or arms, anemia, increased liver enzymes, diarrhea, joint pain, swelling of sinuses, and fatigue.

The most common side effects of NEXLIZET in people with heart problems include kidney problems, anemia, increased liver enzymes, muscle spasms, and gallstones.

These are not all the possible side effects of NEXLIZET. For more information, ask your doctor or pharmacist.

NEXLETOL can cause side effects that can become serious, including:

• increased levels of uric acid in the blood, which can lead to gout, a painful joint condition. Call your doctor if you have any of the following symptoms:
  • severe foot pain, especially in the toe joint
  • warm joints
  • swelling
  • tender joints
  • joint redness
• tendon rupture or injury. Tendon problems can happen in people who take bempedoic acid, one of the medicines in NEXLETOL. The risk of getting tendon problems while you take NEXLETOL is higher if you are over 60 years of age, are taking steroids, are taking antibiotics called fluoroquinolones, have renal failure, or have had tendon problems in the past. Stop taking NEXLETOL immediately and get medical help if you experience signs of tendon rupture, such as snap or pop in tendon area, bruising after an injury in a tendon area, or unable to move or put weight on the affected area

The most common side effects of NEXLETOL in people with high cholesterol include symptoms of the common cold or flu-like symptoms, muscle spasms, back pain, stomach pain, bronchitis, pain in shoulder, legs, or arms, anemia, and increased liver enzymes.

The most common side effects of NEXLETOL in people with heart problems include kidney problems, anemia, increased liver enzymes, muscle spasms, and gallstones.

These are not all the possible side effects of NEXLETOL. For more information, ask your doctor or pharmacist.

Tell your doctor if you:

• have, or had, gout
• have, or had, tendon problems
• are pregnant or breastfeeding or may become pregnant or plan to breastfeed. It is not known if NEXLIZET passes into your breastmilk
• have severe kidney or severe liver problems

Tell your doctor if you:

• have, or had, gout
• have, or had, tendon problems
• are pregnant or breastfeeding or may become pregnant or plan to breastfeed. It is not known if NEXLETOL passes into your breastmilk
• have severe kidney or severe liver problems

Take NEXLIZET or NEXLETOL exactly as your doctor tells you to take it. NEXLIZET and NEXLETOL should be taken once daily, with or without food.

For NEXLIZET: Do not take more than 1 dose per day. If you miss a dose, take the missed dose as soon as possible. Do not double the next dose.

For NEXLIZET: Swallow the NEXLIZET tablet whole. Do not cut, chew, or crush the tablet.

If you take a medicine that lowers cholesterol by binding bile acids, such as colesevelam or cholestyramine, take NEXLIZET at least 2 hours before, or 4 hours after, you take bile acid binding medicines. Ask your doctor if you are not sure if you take these medicines.

If you take NEXLIZET or NEXLETOL, you should also eat a heart-healthy diet. Talk to your doctor about an appropriate diet for you.

NEXLIZET can be taken alone or in combination with other cholesterol-lowering medications, like a statin.

NEXLETOL is used in combination with other cholesterol-lowering medications like a statin, or alone if you are unable to take other cholesterol-lowering medications.